Hepatitis B Virus Test (HBV test) examines substances in the blood to confirm current or past hepatitis B infection. This test can detect signs or indicators of different infections. If antigens or antibodies of hepatitis B virus are detected in the body, the presence of hepatitis B virus may have been infected a long time ago but have recovered, or have recently been infected. Genetic material (DNA) of hepatitis B virus also indicates that the virus is still present in the body, and the content of viral DNA helps to confirm the severity and contagion of infection.
Patients often have both hepatitis B and hepatitis D virus (HDV), known as co-infection. There is no vaccine to prevent hepatitis D. However, it can only be acquired after hepatitis B infection, so hepatitis B vaccine can prevent hepatitis D.
Initial Hepatitis B Virus Test
Hepatitis B surface antigen (HBsAg): Detects proteins on the surface of the virus to detect acute or chronic , HBV carrier state, and identify patients whose symptoms have not yet appeared. However, this test will not work if the patient is in the recovery period.
Hepatitis B surface antibody (anti-HBs): used to detect prior infection with hepatitis B virus, whether A new hepatitis B vaccine is required, or if hepatitis B has recovered and immunized.
Hepatitis B core antibody (Total anti-hepatitis B core, anti-HBc): detection of immunoglobulin G (IgG infection during Antigens are produced and usually remain permanently in the body), and protein M (IgM, the first antibody produced by the body after infection with the virus) can detect acute or chronic hepatitis B infection.
Subsequent testing items after infection with hepatitis B virus
IgM (Anti-hepatitis B core IgM, anti-HBc IgM): Detects only the presence of IgM in the body and is commonly used for Detects acute infections, but is sometimes used to detect chronic infections.
Hepatitis B e-antigen (Hepatitis B e-antigen (HBeAg): Detects proteins produced in the body and released into the blood, which is the infectious power of the hepatitis B virus indicators, can also be used to grasp the effect of the treatment. Some types of viruses do not produce e-antigen and are therefore not detectable, especially in the Middle East or Asia.
Anti-hepatitis B E antibody (Anti-HBe): E antibodies appear along with core and surface antibodies and can be used in Monitoring of recovering acute hepatitis B condition.
Hepatitis B viral DNA: A positive test indicates that the virus is proliferating in the body and is highly contagious. This test is also commonly used to monitor the efficacy of antiviral therapy in patients with chronic hepatitis B.
Hepatitis B virus resistance mutations (Hepatitis B virus resistance mutations): Detects the mutation of the virus causing hepatitis B. Allows the virus to produce antibodies to the course of treatment (reverse transcriptase inhibitors, Reverse transcriptase inhibitors). This test helps patients choose the right course of treatment, especially for those who have already been treated or have no effect on previous treatment.
Why do I need a Hepatitis B Virus Test?
It is important to detect which hepatitis virus you are suffering from, because it prevents transmission to others and allows you to receive appropriate treatment.
Before testing for hepatitis B virus
You do not have to be prepared. If you have any concerns, ask your doctor for more information about the testing needs, risks, and the testing process.
The process of testing for hepatitis B virus
Blood pumping is required for this test. Professional healthcare professionals will extract blood from the vein. After 20 to 30 minutes of blood pumping, you can tear off the tape and cotton. Your doctor will inform you of the time of the test report and explain the results.
Treatment of chronic infections after Hepatitis B Virus Test
If the initial and subsequent examination shows chronic hepatitis B, the patient needs to receive medication and monitor the efficacy of the treatment. Three tests are usually performed for hepatitis B e antigen, hepatitis B e antibody, and hepatitis B virus deoxyribonucleic acid. If the test results are negative for e antigen and positive for e antibody, the treatment is effective and the treatment can be stopped for another 6 to 12 months.
The hepatitis B virus DNA test measures the number of viruses in the blood. If the results show, the more the virus is replicating, which means that the treatment is ineffective. Conversely, if it is low enough to detect, or no virus is detected, it means that there are too few or no viruses in the blood, concluding that the treatment is effective.
The normal scope of the test results may be different in different laboratories or hospitals. If you have any questions about the results, please consult a doctor.