Erectile Dysfunction (ED), commonly known as impotence, is a patient who cannot maintain an erectile state for a long period of time to satisfy sexual function due to medical assistance It is not possible to accurately estimate the incidence of this symptom. However, it is estimated that about 8% to 10% of the male population aged 18 to 60 years have this problem, although this is not a life-threatening disease , but will have a serious impact on the quality of life of men. Patients with hypertension are more likely to have sexual dysfunction than average people. Studies have shown that hypertension and some antihypertensive drugs have adverse effects on erection, if To investigate the cause, first understand the principle of erection.
Why do you get an erection?
Erection is a physiological reaction arising from the interaction of nerves, blood vessels, hormones and psychological factors. Anatomically, the body of the penis is a sponge, and the left and right two sinus sponges extend from the penis to the Pelvis, which has blood vessels, smooth muscles and dense small spaces in the sponge. Under normal circumstances, only part of the arteries that supply blood to the penis will circulate in order to maintain tissues. When stimulating libido, the brain signals trigger hormonal reactions. The penis artery dilates, so more blood flows into the sponge, and because the blood enters the sponge faster than the veins, and the pressure of the veins keeps the blood in the penis, this reaction It is beneficial to achieve an erection and maintain an erection state. When the brain stops sending signals that evoke libido, the hormonal response ends, when the arterial blood flow returns to normal and the penis regained to a soft state.
How does hypertension affect erectile function?
In addition to physiological mechanisms, arterial dilation generally involves cellular biochemical reactions, so the key elements of erection are normal vascular endothelial cells and nitric oxide; Nitric oxide produced by endothelial cells can help regulate the diastolic or constricted vessels. If hypertension, physiological changes may occur in the vessels; increased blood pressure can cause small tear on the walls of the vessels. During repair, the walls of the vessels are thickened, Atherosclerosis forms atherosclerosis and reduced blood flow, which limits blood flow on the penis, and can cause erectile dysfunction. In addition, hypertension is one of the reasons for the reduction of nitric oxide content. Nitric oxide can relax and dialyze blood vessels. Over time, chronic hypertensive patients synthesize and release The amount of nitric oxide may decrease, which affects the ability to fully dilate the blood vessels, making the extra blood required for penis hyperemia not transported properly, resulting in impotence.
In addition, male hypertensive patients may also have lower Testosterone concentrations, which are the main hormone in men and play an important role in libido if testosterone Too low levels can lead to a decrease in the hormonal response to libido.
Relationship between hypotensive drugs and erectile dysfunction
In addition to the above mentioned, hypotensive drugs can also cause sexual dysfunction. Although there are differences in efficacy between different drugs, most hypotensive drugs are somehow associated with erectile dysfunction, especially Diuretics and beta-blocker. Diuretics may cause reduced blood flow into the penis and cause erectile dysfunction. In addition, diuretics may reduce Zinc content in the body. Zinc is an important ingredient for testosterone. The side effects of diuretics are stopped after discontinuation of the drug. Type B blockers can interfere with the nerve impulses that cause erectile reactions. The drug can cause the penis sponge to be soft enough, make the penis artery more difficult to dilate and blood flow, and type B blockers can also cause mild sedation or melancholy, so that libido decreases, and thus derivative dysfunction.
In addition, the mental state of men, such as stress and anxiety, also affects erectile function, so in patients with hypertension, impotence can also be caused by personal psychological factors. One study shows that patients with clear side effects are more likely to develop sexual dysfunction than those with unclear knowledge, personal awareness of health, medication, and psychological adjustment can all be different between the beds. with varying degrees of impact. Overall, erectile dysfunction in patients with hypertension may be caused by vascular changes, drug side effects, or may be related to stress, depression, if you have hypertension and have erectile dysfunction condition, don’t be too nervous and impatient. Talk to your doctor to improve your symptoms.