Drug Facts : Clavulanate is often used to treat inflammation caused by bacterial infections such as sinusitis, pneumonia, otitis media, bronchitis, urinary tract infections and skin infections such as cellulitis. The main purpose of Clavulanate is to prevent the growth of bacteria. This antibiotic is intended only for the treatment of diseases caused by bacterial infections, and not for illnesses caused by viruses, such as common colds, and flu.

How to save Clavulanate?

Clavulanate is best kept at room temperature, dry, and protected from light. Do not keep drugs in the bathroom or in the refrigerator to prevent damage. Different brands of Clavulanate can be stored in different ways, so be sure to read the medication manual or consult your pharmacist to find out how to save it. For safety, please keep the medicine out of reach of children and pets. Unless instructed by a physician or pharmacist, Clavulanate should not be flushed into the toilet or poured into the sink.

Precautions and contraindications to use of Clavulanate

Consult or inform your doctor or pharmacist if:

Pregnant or breastfeeding: Pregnant or breastfeeding women may take medication only with medical advice.
Other medicines being taken: including any non-prescription drugs, herbs and supplements or nutritional products.
Has an allergic reaction to Clavulanate or other medicines.
Tell your doctor about your medical history, including other diseases you are suffering or have had.

Does it affect pregnant women or nursing mothers?

There are not enough studies that suggest that Amoxicillin and Clavulanate are at risk to pregnant women or nursing mothers, but consult a physician before taking medication to measure the potential efficacy and risk of the drug.

According to the U.S. Food and Drug Administration (FDA) classification system for pregnancy use, this drug is rated B.

A: No risk
B: Mild risk
C: Medium risk
D: High risk
X: Absolute prohibition
N: Unknown

Potential side effects of Clavulanate

The following side effects may occur with Clavulanate, but not for everyone, and all possible side effects are not included below. Ask your doctor or pharmacist if you have any concerns.

Clavulanate may have the following side effects, such as:

Mild diarrhea, inflated belly, stomach ache.
Nausea, vomiting.
Rash or itchy.
White spots appear in the mouth or throat.
Vaginal mold infection, for example: itching or the appearance of secretions.

Notify your doctor immediately if any of the following symptoms occur:

Severe rash.
dyspnea, dysphagia.
Vaginal itching and appearance of secretions.

Potential interactions with Clavulanate

What drugs interact with Clavulanate?

Clavulanate may cause an interaction with the drug you are taking, affecting the absorption of the drug or causing serious side effects. To avoid any potential interaction, you should list all medications being used, including prescription, non-prescription and herbal products, and inform physicians and pharmacists. For safety purposes, do not change or discontinue drugs without the consent of your doctor.

Drugs that may interact include:

Probenecid:May lead to increased concentrations of medicine in the blood and prolonged efficacy.
Oral Anticoagulants:The dose of oral anticoagulants needs to be adjusted to maintain the required anticoagulant concentration in the blood.
Allopurinol:Alleplinol is primarily a drug for the treatment of chronic gout. It is not clear that the occurrence of Amoxicillin rash is caused by the taking of alluprolino or hyperuricemia in the patient.
Oral Contraceptives:Potassium in Clavulanate will affects the microflora in the intestine, leading to estrogen metabolism and reducing the effect of oral contraceptives.

Does food and alcohol interact with ?

Clavulanate may interact with food or alcohol, affect drug absorption, or increase the risk of serious side effects. Consult your physician or pharmacist for the interaction of a particular food or alcohol with this drug.

What kind of physical condition affects Clavulanate?

The use of Clavulanate in certain physical conditions may worsen the condition of the body or affect the functioning of the drug. Therefore, it is important for physicians and pharmacists to fully understand their current state of health. Especially if you have:

Liver disease.
Kidney disease.
Other viral infections, such as infectious mononucleosis.

Recommended dose of Clavulanate

The following information does not represent medical advice. Be sure to ask your doctor and pharmacist before taking medication.

Adult Doses

Chewable tablets or Suspension

Adults, adolescents and children weighing more than 40 kg: the recommended dose is 250 to 500 mg per 8 hours, or 500 to 875 mg per 12 hours.

Extended-release tablets

The recommended dose is 2000 mg every 12 hours.


Adults, adolescents and children weighing more than 40 kg: the recommended dose is 250 to 500 mg per 8 hours, or 500 to 875 mg per 12 hours.

Doses for children

Chewable tablets or Suspension

Children older than 3 months and weighing less than 40 kg: how much the dose depends on weight and must be directed by a physician. The recommended dose is usually 20 to 40 mg per kg of body weight once every 8 hours, or 25 to 45 mg per kg per day every 12 hours.

Infants under 3 months: how much the dose depends on weight and must be directed by a doctor. The recommended dose is usually 30 mg per kg of body weight per day, once every 12 hours.

Extended-release tablets

Use and dosage must be directed by a physician.


Children weighing less than 40 kg: the manner of use and dosage must be directed by a physician.
Drug forms of amoxicillin and clavulite potassium

Oral Suspension

125mg /31.25mg / 5ml
200mg /28.5mg / 5ml
250mg /62.5mg / 5ml
400mg /57mg / 5ml
600mg /42.9mg / 5ml


250mg / 125mg
500mg / 125mg
875mg / 125mg

Long-lasting Tablets

1000 mg/62.5 mg

Chewable Tablets

200 mg/28.5 mg
400 mg/57 mg

Overdose or sudden condition

If you have an overdose or a sudden condition, please visit the nearest emergency immediately.

Missed time for medication

If you miss a dose, take it up as soon as possible. However, if you are close to the next scheduled medication, skip the missed time and take the following tablet that you are scheduled to take. Do not use twice the dose.

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