When we take medication before and after eating, the foods or drinks may interact with the drug, which can change the way the drug works in the body. This is called the interaction between foods and the drug. Food can affect the extent and speed at which the drug is absorbed, broken down and excreted by the body, which not only hinders the effective operation of the drug, but also causes side effects.

A wide variety of foods/drinks that may interact with drugs are some of the examples below.


No matter what kind of drug you are taking, avoid alcohol, as it can increase or reduce the effects of many medications.

Caffeinated foods

Coffee, tea, soda and other energy drinks all contain caffeine. Caffeine stimulates the central nervous system, raises blood pressure and also produces diuretic effects. Caffeine eventually breaks down in the liver, and many drugs interfere with liver function, which in turn raises caffeine levels in the blood. Ciprofloxacin, simitin and oral contraceptive pills are examples. Ciprofloxacin and the injectable form of simitin are prescription drugs; but the oral dosage form of simitide is a non-prescription drug. Most oral contraceptives are over-the-counter, but some oral contraceptives are prescription drugs and require a doctor’s prescription.

Caffeine, on the other hand, also inhibits the metabolism of certain drugs, such as tea base, which increases levels of tea base in the blood, which in turn induces side effects of caffeine, including insomnia and arrhythmia. This drug should be sold under the supervision of a pharmacist.

Current article: Knowledge on Medicines – Drug Interactions with Foods and Beverages

Calcium-containing foods

Calcium helps teeth and bones grow and remains robust. Dairy products (such as milk, cheese, cheese and ice cream), green leafy vegetables and tofu are rich in calcium. Today, there are more and more calcium-added fruit juices, breakfast cereals, soy products (such as soy milk) or dairy products (e.g. milk, cheese) on the market. Calcium in food may reduce the body’s ability to absorb drugs. Typical examples include four-cyclocycline, ciprofloxacin, and loxyfluoxacin, which may be reduced when taking calcium-rich foods. In addition, some drugs with low availability, such as bisphosphonates (i.e., arunnial, lisephonate, and banphorate), are also particularly affected by these foods. These drugs that interact with calcium are prescription drugs; Avoid foods or supplements rich in calcium at the same time, and it is recommended to separate the intake time for at least 30 minutes.

Some drug may raise levels of calcium in the body from foods, such as acids (e.g. calcium carbonate), pyridine diuretics (hydrochloroquine, pyridolamine, metolaz), lithium and thyroxine. Acids are over-the-counter drugs, while pyrethroids, lithium and thyroxine are prescription drugs. When taking these drugs, if you eat calcium-rich foods, you should pay more attention to avoid high levels of calcium in your body, which can lead to nausea and vomiting, urination, constipation, abdominal pain, and even cramping and coma.

Juice: grapefruit juice, apple juice and orange juice

Grapefruit juice is a juice known to interact with drugs. Grapefruit juice inhibits an enzyme in the intestines, reducing the metabolism of the drug and increasing the risk of side effects. Drugs that interacts with grapefruit juice includes: statin cholesterol-lowering drugs (and erythropoietin products), blood pressure-lowering drugs (e.g. calcium channel blockers such as amrazto, nitrobenzene and verapammi), oral contraceptives containing estrogen, tricyclic antidepressants (e.g. amitiline and chloramide), cyclosporine, antimalarial drugs (e.g. quian) used to prevent organ transplant rejection. Most of these many drugs that interact with grapefruit juice are prescription drugs. However, oral contraceptives are mostly over-the-counter, and only some oral contraceptives are prescription (also mentioned above). Statins are prescription drugs, including pharmaceutical products containing loffattin.

Another example of how fruit juices may interact with drugs is apple juice and orange juice. The two juices compete with the drug to be absorbed, which lowers its absorption rate.When taking non-sonamine (an antihistamine), such as orange juice and apple juice, its absorption will drop slightly. Other antihistamines, such as citrilquins and chlorpyrifos, may also be affected, but not to the extent that they are non-Sonadine. Non-sona must be sold under the supervision of a pharmacist, while citroquinone can be sold on open shelves at pharmacies. Chlorreta is set to be sold under the supervision of a pharmacist in general, but if chloretre is necessarily included in pharmaceutical products marked only for the relief of symptoms of allergic rhinitis, it can be sold on open shelves.

Red Yeast Rice

“Red Yeast Rice” (abbreviated: RYR) is obtained from fermenting rice with some specific fungi. Red Yeast Rice is grainy in shape, but brittle; The color is fuchsia or brownish-red. It gives the fingers a color and has a sour taste.

Some drugs may react with common foods containing red rice or health products may contain invariable portions of “lovastatin”. People who take erythema-containing products should be cautious because they may feel a drug effect similar to lovastatin;

The ingredient of lofatin itself affects liver function. Pregnant women or nursing mothers should not take pharmaceutical products containing lovastatin. In fact, red crice products (including lovastatin) also have the opportunity to affect the liver. Patients with liver disease, pregnant women or nursing mothers should exercise special care when eating red rice products.

Lovastatin itself may interact with other drugs and not just some foods and beverages; For example, pharmaceutical products containing lovastatin should not be taken with drugs that may inhibit liver enzymes (e.g. isoconazole, ketoconazole, erythromycin, gififerze). If taken at the same time, there is a higher risk of muscle inflammation and other side effects.

If you take a drug containing lovastatin, or other cholesterol-lowering drug, but also take erythema, it is possible to increase the effect of lowering cholesterol to varying degrees (overlay). If you are taking erythema, please tell your doctor so that he or she can give you appropriate advice.

Potassium-containing foods

Some foods such as beans and peas, nuts, fruits (such as bananas, oranges, avocados), green leafy vegetables, white lentils and salts, are rich in potassium. Potassium is an important nutrient to maintain the balance between body fluids and electrolytes. Unbalanced levels of potassium in the body are harmful and can cause nausea, vomiting and even a cardiac arrest. Several types of prescription drugs increase potassium levels in the body, such as angiotensin-converting enzyme inhibitors (e.g. Catopli, Renopri, Remipri), tygausins, which is used to treat heart failure, and the potassium-preserving diuretic drug aminophenyl. When taking these medications, avoid high-potassium foods or drink these juices and vegetable soups.

Foods containing tyramine

Tytamine is naturally found in protein-containing foods. The longer the food is stored, the higher the level of tyramine. Increased levels of tyramine can cause blood pressure to soar to dangerous levels. Under normal circumstances, any tyramines that have entered the body break down rapidly in the intestines and liver. However, if enzyme activity is inhibited, blood pressure can rise sharply. Some prescription drugs interfere with the metabolism of tytise, such as monoamine oxidase inhibitors, including: chlorpyrifos (antidepressants), linamine (antibacterial drugs) and isoniazid (anti-tuberculosis drugs).

Fermented foods, smoked foods, and bad or misstocked foods can all contain tyramine. When taking with  drug, avoid eating large amounts of cheeseamine-rich foods and drinking these beverages at the same time. Please refer to foods and beverages with high levels of tyramine listed below.

List of foods that you need to do portion control upon taking certain drug medication:

Beef or chicken liver, dried meat intestines
Avocados, bananas, dried fruits (e.g. raisins and simeidris)
Red wine
Cheese,  Cheesemade with baste-sterilised milk, including American Cheese, Mita Cheese, Lida, Cheese, Farm Cheese and Chipotle, has a lower chance of high levels of tyramine
Pickled meats, i.e. meats treated with salt and nitrates or nitrites, such as dried summer sausages, pepper sausages and salmeric sausages
Pickles such as German pickles and Korean kimchi
Fermented soy products, including soy oil, Japanese-style sauce, pasta sauce, rotting milk, miso soup, Japanese soy sauce, natto, soy sauce and tashimi
Fermented seafood products such as fish sauce and shrimp sauce
Yeast-refined sauces such as marmalade and Virgil sauce
Misstocked or bad food
Broad beans, such as broad beans
Alcoholic beverages, especially unsterilized beers, including micro-brewed or bottled beers, are known to contain tyramine.

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